Wednesday, September 17, 2025 / 3:00 PM - 4:00 PM EDT
Topic: 2025 BBANYS Annual Meeting Winning Posters
This session will feature our 3 abstract poster winners from our 2025 BBANYS Annual Meeting. They will present their abstracts and be available for a discussion. We hope to see you there and celebrate our members' great scholarly work.
Poster Title:
A High-Sensitivity Flow Cytometry-Based Assay for Enhanced Detection of RBC Alloantibodies
Presenter:
Annie Qiu
Research Associate
Columbia University Medical Center
Department of Pathology and Cell Biology
Brief Bio:
Annie Qiu is a research associate in the Lab of Transfusion Biology at Columbia University Medical Center. She earned her BS in Biology from Emory University, where she studied tyrosine kinase signaling pathways in pediatric leukemia in Dr. Douglas Graham’s lab. At Columbia, as a research technician under Dr. Krystalyn Hudson, she investigated alloimmunization following red blood cell (RBC) transfusions. Now working with Dr. Eldad Hod and Dr. Lisa Eisler as a clinical research coordinator, Annie leads studies on iron deficiency and RBC transfusions. Her work integrates her laboratory expertise with clinical research experience, with a focus on improving transfusion safety and advancing patient care.
Abstract:
Routine agglutination-based assays detect only ~30% of induced red blood cell (RBC) alloantibodies, missing low-titer or evanescent antibodies and posing risks such as hemolytic disease, transfusion reactions, and transplant incompatibility. We developed a multiplex flow cytometry assay designed to improve sensitivity and reproducibility for detecting RBC alloantibodies. Compared with standard agglutination, the flow assay detected a positive sample to a 1:1600 dilution versus 1:128, with distinct cell populations and no signal interference. Reference ranges from 41 healthy controls defined positivity as mean fluorescence intensity >3 SD above the control mean, reproducible across several days. This assay reliably distinguishes between negative, intermediate-, and high-titer samples, offering improved detection of low-titer and evanescent antibodies. By capturing responses that may otherwise go undetected, it has the potential to enhance transfusion safety and inform patient management, though future studies should assess whether increased sensitivity justifies the added complexity and cost of implementation.
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Poster Title:
Successful Platelet Wastage Reduction
Presenter:
Ding Wen Wu, MD, PhD
NYU Langone Hospital - Brooklyn
Brief Bio:
Ding Wen Wu, MD, PhD is a Clinical Professor of Pathology at NYU Grossman School of Medicine, and the Medical Director for Department of Pathology and Laboratory Medicine, at NYU Langone Hospital - Brooklyn, in New York, US. She also holds several other positions at NYU Langone Health. In addition, she is the Medical Director of Blood Bank for SBH Health System, Bronx, New York.
Abstract:
coming
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Poster Title:
Clinical Appropriateness of Von Willebrand Factor Testing in an Academic Medical Center
Presenter:
Bianca Santonastaso
University of Rochester Medical Center
Brief Bio:
coming
Abstract:
coming
Pricing:
- Members: FREE (Registration is required.)
- Non-Members: $45
To receive member pricing, be sure to sign in.
